BDBM50098023 CHEMBL353398::N-(2-Cyano-ethyl)-N-cyclopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-acetamide

SMILES Cn1c(c(CC(=O)N(CCC#N)C2CC2)c2ccccc12)-c1ccccc1

InChI Key InChIKey=WKNJBRUKVOCAEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098023   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098023(CHEMBL353398 | N-(2-Cyano-ethyl)-N-cyclopropyl-2-(...)
Affinity DataIC50:  182nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed