BDBM50098028 CHEMBL366672::N-Isopropyl-N-(1-methyl-1H-pyrazol-3-ylmethyl)-2-(2-phenyl-1H-indol-3-yl)-acetamide

SMILES CC(C)N(Cc1ccn(C)n1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1

InChI Key InChIKey=QCLHANZSCVEOHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098028   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098028(CHEMBL366672 | N-Isopropyl-N-(1-methyl-1H-pyrazol-...)
Affinity DataIC50:  568nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed