BDBM50098033 CHEMBL353527::N-(2-Cyano-ethyl)-N-cyclopropyl-2-[2-(2-methoxy-phenyl)-1H-indol-3-yl]-acetamide

SMILES COc1ccccc1-c1[nH]c2ccccc2c1CC(=O)N(CCC#N)C1CC1

InChI Key InChIKey=KDXGWCXKPZKIHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098033   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098033(CHEMBL353527 | N-(2-Cyano-ethyl)-N-cyclopropyl-2-[...)
Affinity DataIC50:  8.64E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed