BDBM50098034 2-[2-(2-Chloro-phenyl)-1H-indol-3-yl]-N-isopropyl-N-pyridin-4-ylmethyl-acetamide::CHEMBL165823

SMILES CC(C)N(Cc1ccncc1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1Cl

InChI Key InChIKey=PALNUDJZQNISFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098034   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098034(2-[2-(2-Chloro-phenyl)-1H-indol-3-yl]-N-isopropyl-...)
Affinity DataIC50:  46nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed