BDBM50098311 CHEMBL3590408
SMILES CN1CC[C@@H](Nc2ncc(-c3cncc(C)c3)c3cc(C)c(=O)[nH]c23)[C@@H](C1)OCC1CCS(=O)(=O)CC1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 41 hits for monomerid = 50098311
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to ATAD2 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to ATAD2 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2B(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Binding affinity to ATAD2B (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Binding affinity to TAF1 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 126nMAssay Description:Binding affinity to TAF1L (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Binding affinity to BRPF2 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
Affinity DataKi: 794nMAssay Description:Binding affinity to CECR2 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
TargetBromodomain and PHD finger-containing protein 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 794nMAssay Description:Binding affinity to BRPF3 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.01E+3nMAssay Description:Binding affinity to BRPF1 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.94E+3nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+4nMAssay Description:Binding affinity to BRD2 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to BRD3 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+4nMAssay Description:Binding affinity to BRD4 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.16E+4nMAssay Description:Binding affinity to BRD7 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.58E+4nMAssay Description:Binding affinity to BRD9 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to BRPF1 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to KAT2A in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to KAT2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to PBRM1 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+4nMAssay Description:Binding affinity to SMARCA4 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 1.26E+3nMAssay Description:Binding affinity to TAF1 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Binding affinity to BRD2 containing BD1 bromodomains (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Binding affinity to BRD3 containing BD1 bromodomains (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94E+4nMAssay Description:Binding affinity to BRD4 containing BD1 bromodomains (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Binding affinity to BRDt containing BD1 bromodomains (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Binding affinity to ATAD2(unknown origin) by peptide FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Binding affinity to BRD2 containing BD2 bromodomains (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Binding affinity to BRD3 containing BD2 bromodomains (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+5nMAssay Description:Binding affinity to BRD4 containing BD2 bromodomains (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Binding affinity to BRDt containing BD2 bromodomains (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to BPTF in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to BAZ2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2A(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to BAZ2A in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to BAZ1B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2B(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to ATAD2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 63nMAssay Description:Binding affinity to ATAD2 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 200nMAssay Description:Binding affinity to FLAG-6His-Tev-ATAD2 (950 to 1148) (unknown origin) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 200nMAssay Description:Binding affinity to FLAG-6His-Tev-ATAD2 (950 to 1148) (unknown origin) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94E+4nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity to ATAD2 (unknown origin) using HuT-78 chromatin lysate incubated for 2 hrs by bromosphere competition binding assayMore data for this Ligand-Target Pair