BDBM50098919 (R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL7756

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(C(C)C)C(=O)C[C@@H]1C(=O)NO

InChI Key InChIKey=HTNLSTWGHBHDPS-CQSZACIVSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50098919   

TargetCollagenase 3(Rattus norvegicus)
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50:  369nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed