BDBM50098922 (R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-hexahydro-pyrimidine-4-carboxylic acid hydroxyamide::CHEMBL6973

SMILES COc1ccc(cc1)S(=O)(=O)N1CN(C)C(=O)C[C@@H]1C(=O)NO

InChI Key InChIKey=DRWHINQPSIPRHF-LLVKDONJSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50098922   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098922((R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-h...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098922((R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-h...)
Affinity DataIC50:  404nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098922((R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-h...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098922((R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-h...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098922((R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-h...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098922((R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-h...)
Affinity DataIC50:  47nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Rattus norvegicus)
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098922((R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-h...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098922((R)-3-(4-Methoxy-benzenesulfonyl)-1-methyl-6-oxo-h...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed