BDBM50099250 2-[9-ethyl-9-hydroxy-10,13-dioxo-(9S)-2,3,9,10,13,15-hexahydro-1H,12H-[1,4]oxazino[3,2-f]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]acetonitrile::CHEMBL296862

SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc5OCCN(CC#N)c5c4cc3Cn1c2=O

InChI Key InChIKey=AQTJFWBMHPIBIY-DEOSSOPVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099250   

TargetDNA topoisomerase 1(Mus musculus)
Life Science Research Center

Curated by ChEMBL
LigandPNGBDBM50099250(2-[9-ethyl-9-hydroxy-10,13-dioxo-(9S)-2,3,9,10,13,...)
Affinity DataIC50:  1.60E+4nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed