BDBM50099257 6-Chloro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL40680

SMILES F[C@@H]1CCNCC1c1c([nH]c2cc(Cl)ccc12)-c1ccccc1

InChI Key InChIKey=KVZUKTSYJONTHS-OEMAIJDKSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099257   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099257(6-Chloro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-i...)
Affinity DataKi:  2.30nMAssay Description:Ability to displace [3H]-ketanserin binding to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50099257(6-Chloro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-i...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50099257(6-Chloro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-i...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-dofetilide from HEK cells expressing hERG voltage dependent IKr potassium channel Kv11.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099257(6-Chloro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-i...)
Affinity DataKi: >1.60E+3nMAssay Description:Ability to displace [3H]-spiperone binding to CHO cells stably expressing dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed