BDBM50100923 CHEMBL41943::N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-(4'-trifluoromethoxy-biphenyl-4-yloxymethyl)-ethyl]-N-hydroxy-formamide

SMILES CC1(C)NC(=O)N(C[C@H](COc2ccc(cc2)-c2ccc(OC(F)(F)F)cc2)N(O)C=O)C1=O

InChI Key InChIKey=IIHFBHZWJNGWRC-MRXNPFEDSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50100923   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  180nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrilysin(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrilysin(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed