BDBM50101417 CHEMBL539928::[1-Dimethylaminomethyl-2-(1H-indol-3-yl)-1-(1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid benzofuran-2-ylmethyl ester

SMILES C[C@H](NC(=O)[C@@](CN(C)C)(Cc1c[nH]c2ccccc12)NC(=O)OCc1cc2ccccc2o1)c1ccccc1

InChI Key InChIKey=WZOWWAMXPMFHTB-ICACTRECSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101417   

TargetSubstance-P receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101417(CHEMBL539928 | [1-Dimethylaminomethyl-2-(1H-indol-...)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of specific binding at tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101417(CHEMBL539928 | [1-Dimethylaminomethyl-2-(1H-indol-...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101417(CHEMBL539928 | [1-Dimethylaminomethyl-2-(1H-indol-...)
Affinity DataIC50:  5.5nMAssay Description:In vitro affinity for specific binding at Gerbil tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed