BDBM50102222 1-(2-Bromo-phenyl)-3-(7-cyano-3H-benzotriazol-4-yl)-urea::CHEMBL38182

SMILES Brc1ccccc1NC(=O)Nc1ccc(C#N)c2nn[nH]c12

InChI Key InChIKey=SEDUMQWZEOMXSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102222   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50102222(1-(2-Bromo-phenyl)-3-(7-cyano-3H-benzotriazol-4-yl...)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at CXCR2 (unknown origin) expressed in U2OS cells cotransfected with beta-arrestin/TEV protease fusion protein and beta-lactamase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50102222(1-(2-Bromo-phenyl)-3-(7-cyano-3H-benzotriazol-4-yl...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]-IL-8 from CHO cell membranes expressing human CX3C chemokine receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed