BDBM50102478 4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-methoxy-ethyl)-amino]-methyl}-piperidine-1-carboxylic acid 2-methoxy-ethyl ester::CHEMBL315114

SMILES COCCOC(=O)N1CCC(CC1)C(N(CCOC)S(=O)(=O)c1ccc(cc1)-c1ccc(OC)cc1)C(O)=O

InChI Key InChIKey=IIBGHLQTRXDEKI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50102478   

TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  2.65E+3nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  45.5nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  9.10nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  0.600nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  1.22E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50102478(4-{Carboxy-[(4'-methoxy-biphenyl-4-sulfonyl)-(2-me...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed