BDBM50103298 3-[4-(2-Isopropyl-phenylsulfanyl)-3-nitro-phenyl]-1-[4-(pyridine-4-carbonyl)-piperazin-1-yl]-propenone::CHEMBL100372

SMILES CC(C)c1ccccc1Sc1ccc(\C=C\C(=O)N2CCN(CC2)C(=O)c2ccncc2)cc1[N+]([O-])=O

InChI Key InChIKey=OCQSLVRRSSLDCT-CSKARUKUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103298   

TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103298(3-[4-(2-Isopropyl-phenylsulfanyl)-3-nitro-phenyl]-...)
Affinity DataIC50:  66nMAssay Description:Ability to antagonise the Leukocyte function-associated Antigen-1/ Intracellular Adhesion molecule-1 interaction (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed