BDBM50106952 Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester::CHEMBL106803

SMILES [O-][N+](=O)c1ccc(COC(=O)N(CC=C)C2CCN(CCC(Cn3cnc4ccccc34)c3ccccc3)CC2)cc1

InChI Key InChIKey=YQWSBFBPYMXNID-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50106952   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106952(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106952(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50:  4nMAssay Description:Binding affinity against C-C chemokine receptor type 5 stably expressed in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as the radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106952(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106952(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was evaluated for inhibitory activity against C-C chemokine receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106952(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106952(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-X-C chemokine receptor type 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed