BDBM50108058 4'-(2-Amino-3-mercapto-propylamino)-2'-propoxy-biphenyl-3-carboxylic acid 13(FTI-288)::CHEMBL58822

SMILES CCCOc1cc(NC[C@@H](N)CS)ccc1-c1cccc(c1)C(O)=O

InChI Key InChIKey=FSXYFJWXKIMVFY-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108058   

LigandPNGBDBM50108058(4'-(2-Amino-3-mercapto-propylamino)-2'-propoxy-bip...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50108058(4'-(2-Amino-3-mercapto-propylamino)-2'-propoxy-bip...)
Affinity DataIC50:  41nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed