BDBM50108065 4'-(2-Amino-3-mercapto-propylamino)-[1,1';2',1'']terphenyl-3-carboxylic acid 14(FTI-289)::CHEMBL55497

SMILES N[C@@H](CS)CNc1ccc(-c2cccc(c2)C(O)=O)c(c1)-c1ccccc1

InChI Key InChIKey=LEOFHPLVHZUFJS-GOSISDBHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108065   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50108065(4'-(2-Amino-3-mercapto-propylamino)-[1,1';2',1'']t...)
Affinity DataIC50:  20nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50108065(4'-(2-Amino-3-mercapto-propylamino)-[1,1';2',1'']t...)
Affinity DataIC50:  640nMAssay Description:Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed