BDBM50108067 2-Amino-3-[3'-(5H-tetrazol-5-yl)-biphenyl-4-ylamino]-propane-1-thiol 8(FTI-2102)::CHEMBL55639

SMILES N[C@@H](CS)CNc1ccc(cc1)-c1cccc(c1)-c1nnn[nH]1

InChI Key InChIKey=SGQCDCFAFCWKLD-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108067   

LigandPNGBDBM50108067(2-Amino-3-[3'-(5H-tetrazol-5-yl)-biphenyl-4-ylamin...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50108067(2-Amino-3-[3'-(5H-tetrazol-5-yl)-biphenyl-4-ylamin...)
Affinity DataIC50:  30nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed