BDBM50108152 CHEMBL75437::N-[2-(5,5-Dimethyl-2,4-dioxo-imidazolidin-1-yl)-1-(4'-trifluoromethoxy-biphenyl-4-yloxymethyl)-ethyl]-N-hydroxy-formamide

SMILES CC1(C)N(CC(COc2ccc(cc2)-c2ccc(OC(F)(F)F)cc2)N(O)C=O)C(=O)NC1=O

InChI Key InChIKey=ZIOWEXJTMJYIOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108152   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108152(CHEMBL75437 | N-[2-(5,5-Dimethyl-2,4-dioxo-imidazo...)
Affinity DataIC50:  120nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108152(CHEMBL75437 | N-[2-(5,5-Dimethyl-2,4-dioxo-imidazo...)
Affinity DataIC50:  3.70nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108152(CHEMBL75437 | N-[2-(5,5-Dimethyl-2,4-dioxo-imidazo...)
Affinity DataIC50:  4.60E+3nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed