BDBM50109840 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-nitro-phenyl)-N'-cyano-piperidine-1-carboxamidine::CHEMBL158245
SMILES [O-][N+](=O)c1ccc(NC([N-]C#N)=[N+]2CCC(CC2)=C2c3ccc(Cl)cc3CCc3cc(Br)cnc23)cc1
InChI Key InChIKey=IHNGSYVRUWKKEX-UHFFFAOYSA-O
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50109840
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:FPT inhibitory activity was determined by the ability of the compound to inhibit the transfer of [3H]-farnesyl from farnesyl pyrophosphate to H-ras-C...More data for this Ligand-Target Pair