BDBM50109858 4-({[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-piperidine-1-carboximidoyl]-amino}-methyl)-piperidine-1-carboxylic acid amide::CHEMBL440732
SMILES [#7]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#7]-[#6](=[#7]C#N)-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6]-2/c3ccc(Cl)cc3-[#6]-[#6]-c3cc(Br)cnc-23)-[#6]-[#6]-1
InChI Key InChIKey=KJBINAWDNVGVJU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50109858
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:FPT inhibitory activity was determined by the ability of the compound to inhibit the transfer of [3H]-farnesyl from farnesyl pyrophosphate to H-ras-C...More data for this Ligand-Target Pair