BDBM50109874 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-[2-(3H-imidazol-4-yl)-ethyl]-N'-cyano-piperidine-1-carboxamidine::CHEMBL348110
SMILES Clc1ccc2c(CCc3cc(Br)cnc3C2=C2CCN(CC2)C(NCCc2cnc[nH]2)=NC#N)c1
InChI Key InChIKey=MZKNCHCTZBSPNY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50109874
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:FPT inhibitory activity was determined by the ability of the compound to inhibit the transfer of [3H]-farnesyl from farnesyl pyrophosphate to H-ras-C...More data for this Ligand-Target Pair