BDBM50112191 2-(Thiophene-2-carbonyl)-cyclohexanecarboxylic acid [5-(6-cyclopentylamino-purin-9-yl)-4-hydroxy-2-methyl-tetrahydro-furan-3-yl]-amide::CHEMBL53795

SMILES C[C@H]1O[C@H]([C@H](O)[C@H]1NC(=O)C1CCCC[C@H]1C(=O)c1cccs1)n1cnc2c(NC3CCCC3)ncnc12

InChI Key InChIKey=KTJGALBVNCTAAQ-IMMHMDRLSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112191   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50112191(2-(Thiophene-2-carbonyl)-cyclohexanecarboxylic aci...)
Affinity DataKi:  0.720nMAssay Description:GTP-induced shift at rat Adenosine A1 receptor (A1AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50112191(2-(Thiophene-2-carbonyl)-cyclohexanecarboxylic aci...)
Affinity DataKi:  70nMAssay Description:Binding affinity at rat Adenosine A1 receptor in the presence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50112191(2-(Thiophene-2-carbonyl)-cyclohexanecarboxylic aci...)
Affinity DataKi:  98nMAssay Description:Binding affinity at rat Adenosine A1 receptor in the absence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50112191(2-(Thiophene-2-carbonyl)-cyclohexanecarboxylic aci...)
Affinity DataKi:  971nMAssay Description:Binding affinity at human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed