BDBM50113034 (2R,4S)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28942

SMILES ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2cccc(Cl)c2)cc1

InChI Key InChIKey=QUHKOMQMEHKSHH-MAUKXSAKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113034   

LigandPNGBDBM50113034((2R,4S)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50113034((2R,4S)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113034((2R,4S)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibitory concentration of the compound against Matrix metalloproteinase-1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed