BDBM50113036 (2R,4S)-4-Hydroxy-1-[4-(3-methoxy-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29211

SMILES COc1cccc(COc2ccc(cc2)S(=O)(=O)N2CC[C@H](O)C[C@@H]2C(=O)NO)c1

InChI Key InChIKey=HESLKHVXAOLKPX-HNAYVOBHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113036   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113036((2R,4S)-4-Hydroxy-1-[4-(3-methoxy-benzyloxy)-benze...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory concentration of the compound against Matrix metalloproteinase-1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50113036((2R,4S)-4-Hydroxy-1-[4-(3-methoxy-benzyloxy)-benze...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50113036((2R,4S)-4-Hydroxy-1-[4-(3-methoxy-benzyloxy)-benze...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed