BDBM50113047 (2R,4S)-4-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28360

SMILES COc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CC[C@H](O)C[C@@H]1C(=O)NO

InChI Key InChIKey=QXWGXKRGYXQPPV-MAUKXSAKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113047   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113047((2R,4S)-4-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benze...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory concentration of the compound against Matrix metalloproteinase-1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50113047((2R,4S)-4-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benze...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50113047((2R,4S)-4-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benze...)
Affinity DataIC50:  14nMAssay Description:Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed