BDBM50113048 (2R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29007

SMILES ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=GIGWICZCQGBJDH-CRAIPNDOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113048   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113048((2R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-5-hydroxy-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration of the compound against Matrix metalloproteinase-1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50113048((2R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-5-hydroxy-...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50113048((2R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-5-hydroxy-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed