BDBM50113326 (4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanone::CHEMBL78218

SMILES Fc1ccc(CCN2CCC(CC2)C(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=IHYHXNKLWLTICM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50113326   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  9.54nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  63nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  453nMAssay Description:Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  493nMAssay Description:Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  3.00E+3nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed