BDBM50115106 2-(pyridin-2-ylamino)ethane-1,1-diyldiphosphonic acid::CHEMBL294192::[1-Phosphono-2-(pyridin-2-ylamino)-ethyl]-phosphonic acid(NE11808)::[1-phosphono-2-(pyridin-2-ylamino)-ethyl]-phosphonic acid::[2-(2-pyridinylamino)ethylidene]-1,1-bisphosphonate::[2-(PYRIDIN-2-YLAMINO)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)

SMILES OP(O)(=O)C(CNc1ccccn1)P(O)(O)=O

InChI Key InChIKey=BHVCADPDEFLLGM-UHFFFAOYSA-N

Data  3 KI  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115106   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115106(2-(pyridin-2-ylamino)ethane-1,1-diyldiphosphonic a...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115106(2-(pyridin-2-ylamino)ethane-1,1-diyldiphosphonic a...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115106(2-(pyridin-2-ylamino)ethane-1,1-diyldiphosphonic a...)
Affinity DataKi:  36.9nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed