BDBM50115732 CHEMBL294467::Sodium vanadate

SMILES [O-][V](=O)=O

InChI Key InChIKey=ALTWGIIQPLQAAM-UHFFFAOYSA-N

Data  1 KI  4 IC50

PDB links: 16 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115732   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Tampere And Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50115732(CHEMBL294467 | Sodium vanadate)
Affinity DataKi:  5.40E+5nMAssay Description:Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115732(CHEMBL294467 | Sodium vanadate)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50115732(CHEMBL294467 | Sodium vanadate)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human TCPTP using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115732(CHEMBL294467 | Sodium vanadate)
Affinity DataIC50:  46nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115732(CHEMBL294467 | Sodium vanadate)
Affinity DataIC50:  8.05E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluoreacein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed