BDBM50115872 6-Fluoro-2-[2-hydroxy-3-((S)-2-methyl-4,4-dimethyl-cyclopentyloxy)-phenyl]-1H-benzoimidazole-5-carboxamidine::CHEMBL61442

SMILES C[C@H]1CC(C)(C)C[C@@H]1Oc1cccc(-c2nc3cc(F)c(cc3[nH]2)C(N)=N)c1O

InChI Key InChIKey=QAFICSIYHGIBDO-VOJFVSQTSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115872   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115872(6-Fluoro-2-[2-hydroxy-3-((S)-2-methyl-4,4-dimethyl...)
Affinity DataKi:  110nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115872(6-Fluoro-2-[2-hydroxy-3-((S)-2-methyl-4,4-dimethyl...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115872(6-Fluoro-2-[2-hydroxy-3-((S)-2-methyl-4,4-dimethyl...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115872(6-Fluoro-2-[2-hydroxy-3-((S)-2-methyl-4,4-dimethyl...)
Affinity DataKi:  8.30E+4nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115872(6-Fluoro-2-[2-hydroxy-3-((S)-2-methyl-4,4-dimethyl...)
Affinity DataKi:  4.25E+5nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed