BDBM50118071 CHEMBL125967::N-[1-(2-{2-[1-(4-Nitro-phenylcarbamoyl)-2-phenyl-ethylcarbamoyl]-pyrrolidin-1-yl}-2-oxo-ethylcarbamoyl)-ethyl]-succinamic acid

SMILES C[C@H](NC(=O)CCC(O)=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=VSEGOTQZYWBMCQ-TZYHBYERSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118071   

TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Homo sapiens (Human))
Departement D'Ingenierie Et D'Etudes Des Proteines

Curated by ChEMBL
LigandPNGBDBM50118071(CHEMBL125967 | N-[1-(2-{2-[1-(4-Nitro-phenylcarbam...)
Affinity DataIC50:  1.45E+6nMAssay Description:Inhibitory activity against Human Cyclophilin hCyp-18 Peptidyl-prolyl isomerase by using the standard trypsin-coupled PPIase (peptidyl-prolyl isomera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50118071(CHEMBL125967 | N-[1-(2-{2-[1-(4-Nitro-phenylcarbam...)
Affinity DataKd:  1.35E+5nMAssay Description:Binding affinity to CypA (unknown origin) by fluorescence titration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Homo sapiens (Human))
Departement D'Ingenierie Et D'Etudes Des Proteines

Curated by ChEMBL
LigandPNGBDBM50118071(CHEMBL125967 | N-[1-(2-{2-[1-(4-Nitro-phenylcarbam...)
Affinity DataKd:  1.40E+5nMAssay Description:The compound was evaluated for its binding affinity against Human Cyclophilin hCyp-18 Peptidyl-prolyl isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed