BDBM50119321 1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-{3-[4-(1H-tetrazol-5-yl)-phenyl]-propyl}-piperidin-4-ol::1-(1-cyclohexylmethyl-4-phenyltetrahydro-1H-3-pyrrolylmethyl)-4-{3-[4-(1H-1,2,3,4-tetraazol-5-yl)phenyl]propyl}hexahydro-4-pyridinol::4-(3-(4-(1H-tetrazol-5-yl)phenyl)propyl)-1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-ol::CHEMBL319593

SMILES OC1(CCCc2ccc(cc2)-c2nnn[nH]2)CCN(C[C@H]2CN(CC3CCCCC3)C[C@@H]2c2ccccc2)CC1

InChI Key InChIKey=MYTRYQKUDUGKTA-IOWSJCHKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119321   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119321(1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmeth...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119321(1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmeth...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [125I]MIP1alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119321(1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmeth...)
Affinity DataIC50:  0.200nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed