BDBM50120586 CHEMBL112221::Methyl-[2-(pyridin-3-yloxy)-ethyl]-amine::N-methyl-2-(pyridin-3-yloxy)ethanamine::N-methyl-2-(pyridin-3-yloxy)ethanaminium

SMILES CNCCOc1cccnc1

InChI Key InChIKey=HKLZABNBARUZMN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120586   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50120586(CHEMBL112221 | Methyl-[2-(pyridin-3-yloxy)-ethyl]-...)
Affinity DataKi:  35nMAssay Description:Binding affinity towards nicotinic acetylcholine receptor alpha4-beta2 from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50120586(CHEMBL112221 | Methyl-[2-(pyridin-3-yloxy)-ethyl]-...)
Affinity DataKi:  35nMAssay Description:Affinity to alpha-4-beta-2 AChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50120586(CHEMBL112221 | Methyl-[2-(pyridin-3-yloxy)-ethyl]-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed