BDBM50121209 CHEMBL3622376
SMILES C(C1CO1)n1cc(nn1)-c1ncnc2[nH]ccc12
InChI Key InChIKey=SGBZXUCHKSJHOS-UHFFFAOYSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50121209
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of JAK1 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of JAK2 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of TYK2 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of JAK3 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in prese...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG] substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human JAK3 using GGEEEEYFELVKKKK substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in presence ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in prese...More data for this Ligand-Target Pair