BDBM50121209 CHEMBL3622376

SMILES C(C1CO1)n1cc(nn1)-c1ncnc2[nH]ccc12

InChI Key InChIKey=SGBZXUCHKSJHOS-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50121209   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of JAK1 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of JAK2 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  5.62E+3nMAssay Description:Inhibition of TYK2 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  35nMAssay Description:Inhibition of JAK3 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  35nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in prese...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  5.62E+3nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  5.62E+3nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG] substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  35nMAssay Description:Inhibition of human JAK3 using GGEEEEYFELVKKKK substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  35nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121209(CHEMBL3622376)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in prese...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed