BDBM50121327 CHEMBL3622089::US10562882, Example 27

SMILES CCn1c(cc2cc(Cl)ccc12)C1CCCN(C1)C(=O)c1cn(C)nc1N

InChI Key InChIKey=DIEDLVNTPMBIMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121327   

TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50121327(CHEMBL3622089 | US10562882, Example 27)
Affinity DataIC50:  910nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50121327(CHEMBL3622089 | US10562882, Example 27)
Affinity DataIC50:  910nMAssay Description:Antagonist activity at human PKR1 expressed in rat RBL2H3 cells assessed as inhibition of PK1-stimulated intracellular calcium release incubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed