BDBM50121987 CHEMBL153254::[3-(2-Chloro-6-methylamino-purin-9-yl)-2-phosphonomethyl-propyl]-phosphonic acid

SMILES CNc1nc(Cl)nc2n(CC(CP(O)(O)=O)CP(O)(O)=O)cnc12

InChI Key InChIKey=FFBIISIICFTESN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50121987   

TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50121987(CHEMBL153254 | [3-(2-Chloro-6-methylamino-purin-9-...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50121987(CHEMBL153254 | [3-(2-Chloro-6-methylamino-purin-9-...)
Affinity DataIC50:  617nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50121987(CHEMBL153254 | [3-(2-Chloro-6-methylamino-purin-9-...)
Affinity DataIC50:  620nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed