BDBM50124593 5-Allyl-2,2,4-trimethyl-10-methylsulfanyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL8394

SMILES CSc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key InChIKey=XTULGNRZXMHXPU-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124593   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124593(5-Allyl-2,2,4-trimethyl-10-methylsulfanyl-2,5-dihy...)
Affinity DataEC50:  18nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124593(5-Allyl-2,2,4-trimethyl-10-methylsulfanyl-2,5-dihy...)
Affinity DataEC50:  123nMAssay Description:Inhibition of dihydrofolate reductase DHFR in Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed