BDBM50124975 2-[4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide::CHEMBL423810

SMILES Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)N1CCN(CC(=O)NC(CCCNC(N)=N)C(=O)c2nccs2)C(=O)C1

InChI Key InChIKey=MNVVFWIYSOOEQC-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50124975   

TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124975(2-[4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfon...)
Affinity DataKi:  0.170nMAssay Description:In vitro binding affinity towards factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124975(2-[4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfon...)
Affinity DataIC50:  0.510nMAssay Description:In vitro inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124975(2-[4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfon...)
Affinity DataIC50:  9.96E+3nMAssay Description:Inhibitory activity against tissue plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124975(2-[4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfon...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124975(2-[4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfon...)
Affinity DataIC50:  1.69E+5nMAssay Description:Inhibitory activity against activated protein C (aPC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124975(2-[4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfon...)
Affinity DataIC50:  751nMAssay Description:In vitro inhibitory activity against serine protease thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124975(2-[4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfon...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed