BDBM50125741 8a-Benzyloxymethyl-6-furan-2-yl-1,4-dioxo-2-(4-phenyl-butyl)-octahydro-pyrrolo[1,2-a]pyrazine-7-carboxylic acid methyl ester::CHEMBL14207

SMILES COC(=O)C1CC2(COCc3ccccc3)N(C1c1ccco1)C(=O)CN(CCCCc1ccccc1)C2=O

InChI Key InChIKey=HSVVVXHRAQHIAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125741   

TargetHormone-sensitive lipase(Homo sapiens (Human))
Ontogen

Curated by ChEMBL
LigandPNGBDBM50125741(8a-Benzyloxymethyl-6-furan-2-yl-1,4-dioxo-2-(4-phe...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against human hormone-sensitive lipase (HSL) expressed in the baculovirus was determined by p-nitrophenyl butyrate (PNPB) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Ontogen

Curated by ChEMBL
LigandPNGBDBM50125741(8a-Benzyloxymethyl-6-furan-2-yl-1,4-dioxo-2-(4-phe...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against Human Hormone-sensitive lipase (HSL) expressed in the baculovirus was determined by HSL [14 C] cholesteryl oleate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed