BDBM50126127 CHEMBL3628943

SMILES CCCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(nn1)[C@@](C)(NCc1ccn2nccc2n1)C1CCCC1

InChI Key InChIKey=GJWDUYBKAOXWIS-JKDDQTOVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126127   

TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126127(CHEMBL3628943)
Affinity DataIC50:  263nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50126127(CHEMBL3628943)
Affinity DataIC50:  3nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50126127(CHEMBL3628943)
Affinity DataIC50:  3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzain using Z-FR-AMC as substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed