BDBM50126144 CHEMBL3629569::US10155972, Compound NewLink 1::US10233190, Example 1304

SMILES OC(CC1c2ccccc2-c2cncn12)C1CCCCC1

InChI Key InChIKey=YTRRAUACYORZLX-UHFFFAOYSA-N

Data  1 KI  21 IC50  1 Kd  3 EC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126144   

TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Iomet Pharma

US Patent
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)
Affinity DataIC50:  501nMAssay Description:In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Iomet Pharma

US Patent
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)
Affinity DataIC50:  398nMAssay Description:In two separate assays, 0.045 μg/μl of human IDO protein was pre-incubated for 10 min at RT with test compounds NewLink 1 and Incyte 1 in t...More data for this Ligand-Target Pair
In DepthDetails US Patent