BDBM50126319 4-Cyano-5-naphthalen-1-yl-3,6-dihydro-2H-pyridine-1-carboxylic acid (3,4-dichloro-benzyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amide::CHEMBL284637

SMILES Cn1cncc1CN(Cc1ccc(Cl)c(Cl)c1)C(=O)N1CCC(C#N)=C(C1)c1cccc2ccccc12

InChI Key InChIKey=KVWMCWMRPHPVTC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126319   

TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50126319(4-Cyano-5-naphthalen-1-yl-3,6-dihydro-2H-pyridine-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of geranylgeranyltransferase-1More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50126319(4-Cyano-5-naphthalen-1-yl-3,6-dihydro-2H-pyridine-...)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:In vitro inhibition of farnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI