BDBM50126572 CHEMBL35754::N-[1-(2,4-Bis-trifluoromethyl-phenyl)-ethyl]-2-[3-(4-carbamimidoyl-phenyl)-ureido]-acetamide

SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1C(F)(F)F)C(F)(F)F

InChI Key InChIKey=DMOHNDKXEKUKGV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126572   

TargetCoagulation factor VII(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50126572(CHEMBL35754 | N-[1-(2,4-Bis-trifluoromethyl-phenyl...)
Affinity DataKi:  27nMAssay Description:In vitro inhibitory activity against coagulation factor VII (fVIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50126572(CHEMBL35754 | N-[1-(2,4-Bis-trifluoromethyl-phenyl...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibitory activity against zymogen coagulation factor (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50126572(CHEMBL35754 | N-[1-(2,4-Bis-trifluoromethyl-phenyl...)
Affinity DataKi: >1.00E+5nMAssay Description:In vitro inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed