BDBM50127798 CHEMBL50374::Thiophene-2-carboxylic acid [2-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-amide

SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccs1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=UKFQHKRZVDHZEX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127798   

TargetATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127798(CHEMBL50374 | Thiophene-2-carboxylic acid [2-(2,2,...)
Affinity DataEC50:  12nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed