BDBM50128344 CHEMBL3629177

SMILES COc1ccc(Nc2nc3cc(NC(=O)CCCCOc4ccc(cc4)C(\N)=N\O)ccc3o2)cc1

InChI Key InChIKey=HFTRNYFARDMCBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128344   

TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)
Affinity DataIC50:  580nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed