BDBM50129160 9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::9-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline::CHEMBL65522

SMILES COc1ccc2OCc3c(ccc4NC(C)(C)C=C(C)c34)-c2c1

InChI Key InChIKey=GHHQOEGOQYZOJT-UHFFFAOYSA-N

Data  2 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50129160   

TargetProgesterone receptor(Homo sapiens (Human))
Scientific Computing

Curated by ChEMBL
LigandPNGBDBM50129160(9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]progesterone from Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Scientific Computing

Curated by ChEMBL
LigandPNGBDBM50129160(9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataKi:  86nMAssay Description:Binding affinity at human progesterone receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Scientific Computing

Curated by ChEMBL
LigandPNGBDBM50129160(9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration for human progesterone receptor in T47D human breast cancer cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Scientific Computing

Curated by ChEMBL
LigandPNGBDBM50129160(9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataIC50:  187nMAssay Description:Inhibition of human progesterone receptor activation in T47D human breast cancer cell.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Scientific Computing

Curated by ChEMBL
LigandPNGBDBM50129160(9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataEC50:  170nMAssay Description:Antagonistic activity at human progesterone receptor in CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed