BDBM50131529 3-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-propionamide::CHEMBL97762

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)NCCC(=O)NO

InChI Key InChIKey=LXSYXSGOVAASBA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131529   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131529(3-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Matrix metalloprotein-9 at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131529(3-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Matrix metalloprotein 1 at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131529(3-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50:  145nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131529(3-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50:  37nMAssay Description:Inhibition of Matrix metalloprotein 13 at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed