BDBM50131949 2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethyl-2,5-dioxo-imidazolidin-1-ylmethyl)-cyclopentanecarboxylic acid::CHEMBL126712

SMILES CC1(C)NC(=O)N(C[C@@H]2CC[C@H](Sc3ccc(cc3)-c3ccc(Cl)cc3)[C@H]2C(O)=O)C1=O

InChI Key InChIKey=DRINIAFHXKEERM-VDGAXYAQSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131949   

TargetStromelysin-1(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131949(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethy...)
Affinity DataIC50:  9.40nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131949(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethy...)
Affinity DataIC50:  572nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131949(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethy...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131949(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethy...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131949(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethy...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed