BDBM50134557 3-(4-Cyano-phenylethynyl)-4-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-benzonitrile::CHEMBL124081

SMILES Cn1cncc1C(OCc1ccc(cc1C#Cc1ccc(cc1)C#N)C#N)c1ccc(cc1)C#N

InChI Key InChIKey=WHPKJYJVLZBIAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134557   

LigandPNGBDBM50134557(3-(4-Cyano-phenylethynyl)-4-[(4-cyano-phenyl)-(3-m...)
Affinity DataIC50:  0.630nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50134557(3-(4-Cyano-phenylethynyl)-4-[(4-cyano-phenyl)-(3-m...)
Affinity DataIC50:  124nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed